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The Ecosystems Research Division [ERD] of the of the Office of Research and Development's National Exposure Research Laboratory conducts process, modeling, and field research to assess the exposure risks of humans and ecosystems to chemical and non-chemical stressors. Leading-edge computational technologies are developed to integrate core sciences into multi-media (air, surface water, ground water, soil, sediment, biota), multi-stressor, and multi-scale (organism, population, community, ecosystem; field, site, watershed, regional, national, global) modeling systems that provide predictive capabilities for complex environmental exposures. ERD supports the EPA's mission by developing innovative methods and associated software tools for evaluating modeling systems, including uncertainty analysis, sensitivity analysis, and parameter estimation for simple and complex environmental models. For additional information regarding ERD, visit its home page at http://www.epa.gov/athens/.