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The Chagas Disease Foundation was established to promote the diagnosis, control, prevention, and treatment of Chagas disease. The Foundation will use its resources to facilitate scientific research, to educate and train researchers, to disseminate information on control and prevention, and for the development of policies for the sustainable prevention of Chagas disease. Chagas disease has been described as the most neglected of all neglected tropical diseases. The Chagas Disease Foundation grew out of a concern with this current situation and the relative lack of attention and effort that the disease receives. Our efforts begin with education. We believe that significant and rapid progress on the detection, treatment and prevention of Chagas disease is possible, but only with better information, more collaborations and greater funding for research, training and intervention efforts. Our hope is that by raising awareness we can generate more resources to combat Chagas disease.