AIF's mission is to accelerate social and economic change in India. By mobilizing people and resources in the United States, AIF has invested in over 100 Indian non-governmental organizations since its inception in 2001. AIF awards grants to education, livelihood and public health projects in India - with emphases on elementary education, women's empowerment and maternal and child health respectively.

AIF also administers two programs: (1) Digital Equalizer, which bridges the"digital divide" by providing computers, Internet access and training in under-resourced schools, and (2) Service Corps, which builds the capacity of Indian NGOs by placing qualified young American professionals for ten-month volunteer assignments. President Bill Clinton serves as Honorary Chair of AIF.