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Sustainable Health Enterprises (SHE), an internationally recognized social venture, invests in people and ideas that are typically overlooked (and often taboo) as vehicles of socio-economic change. SHE's first initiative, SHE28, addresses girls' and women's lack of access to affordable menstrual pads resulting in significant costs to their reproductive health, educational achievements, work productivity, and dignity. SHE is stemming these costs by developing a franchise model to manufacture and distribute affordable, eco-friendly menstrual pads for girls and women by sourcing local, inexpensive raw materials (e.g., banana fibers) and leveraging existing networks. Coupling these new businesses with public health and hygiene education and advocacy will have a significant social and economic impact on these communities.