Runway to Hope was founded in September 2010 with a mission to provide support and help to Central Florida children and their families impacted by pediatric cancer. Its founders, Mark and Josie NeJame, envisioned a charity that would provide direct assistance to those in need, keep the funds local and bring new or underserved services to Central Florida's three children's hospitals.
Through the Family Assistance Program, direct aid is provided to families in emergencies and when needed. Additionally, through partnerships with Arnold Palmer Hospital for Children, Florida Hospital for Children and Nemours Children's Hospital, Runway to Hope brings new programs and initiatives to the pediatric oncology programs in each of these hospitals.