The mission of the Lipedema Foundation is to define, diagnose, and develop treatments for lipedema. The poorly understood disease is a chronic condition that occurs almost exclusively in women, and presents as a buildup of painful fat and swelling in the arms and legs, sparing the hands and feet. Since 2015, the foundation has committed over $5 million dollars towards lipedema research to identify the drivers of disease and develop diagnostic tools. With a focus on collaborative research and transparency, the foundation aims to employ traditional and novel methods to sustainably build the nascent lipedema research community. The Lipedema Foundation is a US 501c3 non-profit and 509a private family foundation, with offices in Connecticut and Maryland.