#ThroughThePain started in 2018 as a T-Shirt fundraiser to aid income during a stem cell procedure. Founders supported SCD Warriors in hospitals and distributed care packs. In 2019, they launched their website and Ambassador Program. 2020 saw a World Sickle Cell Day Virtual Summit and the debut of their podcast. By 2022, they partnered with the Red Cross of Massachusetts, became a 501(c)3 non-profit, and collaborated with the CaRISMA study for SCD Health Coaching. In 2023, they became a CBO Partner with the Sickle Cell Consortium and expanded their partnership with The American Red Cross.